What do we seek above all else? Money? Success? Notoriety?
Money is necessary to live, but it is only a means to an end. Money on its own is worthless. Success is not as sweet if you have no one to share your accomplishments with. Fame is fleeting as there will always come a more talented, smarter, better-looking person after you.
So what should we value above all?
Relationships. They are complicated but it is exactly this that makes everything else in life meaningful.